Effect of the ketogenic diet on glycemic control, insulin resistance, & lipid metabolism in Diabetes

Effect of the ketogenic diet on glycemic control, insulin resistance, and lipid metabolism in patients with T2DM: a systematic review and meta-analysis


  • Published: 30 November 2020

Results

After KD intervention, in terms of glycemic control, the level of fasting blood glucose decreased by 1.29 mmol/L (95% CI: −1.78 to −0.79) on average, and glycated hemoglobin A1c by 1.07 (95% CI: −1.37 to −0.78). As for lipid metabolism, triglyceride was decreased by 0.72 (95% CI: −1.01 to −0.43) on average, total cholesterol by 0.33 (95% CI: −0.66 to −0.01), and low-density lipoprotein by 0.05 (95% CI: −0.25 to −0.15); yet, high-density lipoprotein increased by 0.14 (95% CI: 0.03−0.25). In addition, patients’ weight decreased by 8.66 (95% CI: −11.40 to −5.92), waist circumference by 9.17 (95% CI: −10.67 to −7.66), and BMI by 3.13 (95% CI: −3.31 to −2.95).

Conclusion

KD not only has a therapeutic effect on glycemic and lipid control among patients with T2DM but also significantly contributes to their weight loss.



Link to Full text:

https://www.nature.com/articles/s41387-020-00142-z?utm_source=nutd_etoc&utm_medium=email&utm_campaign=toc_41387_10_1&utm_content=20201201&sap-outbound-id=E49535A68D577B79C13E037DAB8CC7A118ABDE72FL&fbclid=IwAR3uEgw0uAUgoZXp5cNAfhc_FqPapdQ80is3Tv8-XCB9aKJquR3cMjEygb0&s=08


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